Protein Analytics

Services

Protein Activity and Binding:

- Protein activity
- Binding affinity
- Enzyme activity
- Cell-based assays
- In vivo testing

Protein Stability:

- Protein stability
- Tm & Tagg
- ΔG
- Isothermal stability
- Thermal recovery
- Sizing & polydispersity
- Sizing with thermal ramp
- B22 & kD
- Viscosity

Protein Quantification:

- Protein titer/concentration
- Protein A HPLC
- ELISA
- A280

Protein Integrity and Structure:

- Size variants by SEC-HPLC
- Size variants by SEC-MALS
- Size variants by CE-SDS (reduced and non-reduced)
- Hydrophobic variants by RP-HPLC/UPLC or HIC
- Protein purity by SDS-PAGE
- N-glycan analysis by HILIC-FLD
- N-glycan analysis by CE
- Sialic acid content by DMB RP
- Free thiol content by SEC-FLD
- Charge variants by cIEF
- Western Blot

Contaminant Detection:

- HCP titer by ELISA
- Residual Protein A, Protein G, Protein L by ELISA or Octet
- Endotoxin levels by LAL

Mass Spectrometry:

- Protein mass (Agilent HPLC-CHIP/QTOF)
- Accurate mass: proteins, protein-drug conjugates

Additional Services

Consultation for Polymer Companies:

- Formulations and technical aspects for sensors
- Packaging solutions
- Recycling and composting technologies

Our specialized expertise ensures high-quality results, making us the perfect partner for research groups in universities, institutes, and high-tech companies looking to outsource their research and development needs.

- - Peptide and Glycan mapping
  - Determination of post-translations modifications either in known or unknown samples.
  - Standard COAs